Leuven | More than two weeks ago
Learn how to build realistic brain tissue models and test their predictions
Mechanical stability is a crucial requirement for the long-term functioning of recording brain electrodes. Stresses caused by displacements between the tissue and an electrode are believed to be detrimental to the implant’s function. Current simulation results point towards the role of respiration and blood vessel pulsation as main factors interacting with the implant. The topic will develop a technique to estimate forces and pressure exerted on a brain implant during normal physiological activity. As a starting point, the student will refine the existing FEM model of an implant immersed in soft tissue (see image).
Specifically, the student will explore 1) viscoelastic multicompartmental head model to adequately account for different soft and hard tissues (i.e. brain matter, blood vessels, skull) or 2) more realistic blood vessel models in a simplified tissue geometry. Based on the outcome of the simulation study, the student will produce an up-scaled tissue phantom and improve the existing experimental setup.
Type of project: Combination of internship and thesis
Duration: 6 - 9 months
Required degree: Master of Engineering Technology, Master of Engineering Science, Master of Science
Required background: Electromechanical engineering
Supervising scientist(s): For further information or for application, please contact: Dimiter Prodanov (Dimiter.Prodanov@imec.be)