Stem cell technology has opened a myriad of possibilities to study diseases without the use of animals testing and in a human context. Futher, stem cells have a large potential as a therapy. Silicon nanofabricated chips offer a range of functionalities to study and monitor individual stem cells in a non-invasive manner. However, as microchips are mostly planar and rigid structures, there is a mismatch with the growing need for soft and three-dimensional interfacing. This PhD topic will investigate 3D interfacing with individual cells at the micrometer level using kirigami like microstructuring using newly developed process integration steps and materials. The candidate will using Multiphysics modeling in combination with advanced lithography to create novel 3D interfaces. Finally, chips will be tested in threedimensional biological environments.
Required background: physics, bioelectronics, electrical engineering with biological experience
Type of work: 20% literature, 20% modeling, 60% lab or cleanroom work
Supervisor: Liesbet Lagae
Daily advisor: Dries Braeken
The reference code for this PhD position is SE1712-26. Mention this reference code on your application form.